15-20 minutes medical students, residents, fellows, faculty Updated Fri Jun 12 2026 00:00:00 GMT+0000 (Coordinated Universal Time)

Quick Summary

  • New-onset psychotic symptoms in youth require a broad psychiatric, substance-related, and medical differential.
  • Substance-induced psychosis is often more common than primary psychotic illness in acute settings.
  • Developmental context and reality testing matter when interpreting unusual perceptions or beliefs.
  • Red flags include suicidality, severe aggression, catatonia, medical instability, and very young age.
  • Early referral and shorter duration of untreated psychosis are associated with better outcomes.
  • Primary care and consult teams play an important role in recognition, family education, and linkage to treatment.

Resources

Practice Questions

  • What features make you worry that a youth with psychotic symptoms needs urgent medical or psychiatric escalation?
  • How would you distinguish a primary psychotic disorder from substance-induced or medically secondary psychosis in an initial evaluation?

Archived Teaching

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